TV and radio personality Aled Hughes cut the ribbon to officially open the store on Saturday.
Aled was joined by local property developer Rob Lloyd and the rugby team from Bangor University.
The shop, located in Unit 13 of the Menai Centre, opposite Marks and Spencer, is the third Cancer Research Wales shop to open in North Wales this year.
The Llandudno store opened in April, and the Wrexham one in May.
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The store is decorated in Cancer Research Wales’s distinctive coloured stripe branding logo, which is inspired by DNA sequencing gels used by scientists to find cancer cells.
Now open, the shop sells goods including women’s, children’s, and men’s clothing, a range of household items, and bric-a-brac.
Lorraine Boyd, head of retail at Cancer Research Wales, said: “I’d like to say a big ‘thank you’ to Aled Hughes for giving up his time to come and open our brand-new store in Bangor on Saturday.
“It’s a privilege to have him cut the ribbon for us, and we’re very grateful to Aled for his support.
“We’re excited to be coming to Bangor and look forward to our colourful stripe-branded shop becoming a familiar and loved landmark in the city centre—and our own little community within the community, where there’s always a warm welcome.”