Wales prop Henry Thomas has been ruled out of the international against world champions South Africa on Saturday at Twickenham because of a foot injury.
Thomas, who has recently signed for Scarlets, has been replaced by Cardiff prop Keiron Assiratti with Harri O’Connor called on to the replacements bench.
England-based tight-head props Archie Griffin and Dillon Lewis are unavailable because the match falls outside World Rugby’s international window.
Thomas has not been ruled out of the two-Test summer tour of Australia yet with head coach Warren Gatland announcing a final 34-man squad after the South Africa game.
Wales v South Africa: Cameron Winnett; Liam Williams, Owen Watkin, Mason Grady, Rio Dyer; Sam Costelow, Ellis Bevan; Gareth Thomas, Dewi Lake, Keiron Assiratti, Matthew Screech, Ben Carter, Taine Plumtree, James Botham, Aaron Wainwright.
Replacements: Evan Lloyd, Kemsley Mathias, Harri O’Connor, James Ratti, Mackenzie Martin, Gareth Davies, Eddie James, Jacob Beetham.